HCPCS Changes — 2025-Q4

69 new • 9 revised • 95 deleted

New Codes (69)

Code Description
A4288 Replacement breastpump valve
A4453 Rec cath any transanal, each
A4459 Transanal irrigation, any
A9612 Inj, fluorescein, 1 mg
A9616 Gallium gozellix 1 millicuri
C1739 Marker uniq detect w/prbe
C1740 Lt vent pacing syst, sequen
C1742 Pressure sens syst, cont im
C1982 Cath, pressure,valve-occlu
C8006 Inst pleu-perit shnt w pump
C9088 Instill, bupivac and meloxic
C9174 Datopotamab deruxtecan, 1 mg
C9175 Inj, treosulfan, 50 mg
C9248 Inj, clevidipine butyrate
E0150 Combo walker-transport chair
E0658 Seg pneum comp 2 arm chest
E0659 Seg pneum comp head neck che
E0765 Nerve stimulator for tx n&v
E0986 Man w/c powr assist syst
J0163 Epinephrine in nacl (endo)
J0164 Epinephrine in nacl (baxter)
J0458 Aztreonam/avibactam 10 mg
J0525 Inj cefotetan disodium 10 mg
J0570 Buprenorphine implant 74.2mg
J0582 Bivalirudin (endo) 1 mg
J0614 Inj, treosulfan, 50 mg
J0668 Instill, bupivac and meloxic
J0675 Inj, carboprost, 0.1 mg
J0681 Inj ceftobipole medocarl 3mg
J0738 Hiv prep, inj, lenacapavir
J0752 Hiv prep, oral lenacapavir
J1370 Inj, esomeprazole sod, 1 mg
J1612 Inj glucagon (gvoke) 0.01 mg
J1807 Inj, ethacrynate sod, 1 mg
J1809 Inj, fosdenopterin, 0.1mg
J1834 Inj, isoniazid, 1 mg
J2150 Mannitol injection
J2151 Inj, mannitol, 250 mg
J2291 Inj, nafcillin (baxter) 20mg
J2503 Pegaptanib sodium injection
J3290 Inj, tranexamic acid 5 mg
J3402 Inj. remestemcel-l-rknd/ td
J3403 Revakinagene, per implant
J7173 Inj. concizumab-mtci, 0.5 mg
J7174 Injection fitusiran 0.04 mg
J7300 Intra copp contra (paragard)
J9011 Datopotamab deruxtecan, 1 mg
J9072 Inj cyclophos frindovyx 5 mg
J9333 Inj rozanolixizum-noli 1 mg
L1007 Scoliosis orth s-c custom
L5673 Socket insert w lock mech
L5679 Socket insert w/o lock mech
L5783 Add low ext mec limb vol lam
L6034 Part hand finger distal amp
L6035 Prosthetic digit mechanical
L6036 Prosthetic thumb mechanical
L6038 Multiax rotation attachment
L6039 Passive custom digit/thumb
L7406 Add upp ext mec limb vol lam
M0235 Intrav inf, mon anti, fir do
M0236 Intrav inf, mon anti, sec do
Q0235 Inj, monoclon antibody, 1 mg
Q5154 Inj, omlyclo, 5 mg
Q5155 Inj, aflibercept-jbvf, 1 mg
Q5156 Inj, tocilizumab-anoh, 1 mg
Q5157 Inj, denosumab-bmwo, 1 mg
Q5158 Inj, denosumab-bnht, 1 mg
Q5159 Inj, denosumab-dssb, 1 mg
S0074 Injection, cefotetan disodiu

Revised Codes (9)

Code Old Description New Description
C1739 Tissue marker, detectable Marker uniq detect w/prbe
E0986 Man w/c push-rim powr system Man w/c powr assist syst
J1961 Inj, lenacapavir, 1 mg Inj lenacapavir (hiv tx) 1mg
J7300 Intraut copper contraceptive Intra copp contra (paragard)
J9072 Inj cyclophos avyxa 5mg Inj cyclophos frindovyx 5 mg
J9333 Inj ronzanolixizum-noli 1 mg Inj rozanolixizum-noli 1 mg
L5783 Add low ext mec limb vol sys Add low ext mec limb vol lam
L6028 Part handfng endoskel molded Part hand finger metacar amp
L7406 Add to upp extr user adj mec Add upp ext mec limb vol lam

Deleted Codes (95)

Code Description
C5271 Low cost skin substitute app
C5272 Low cost skin substitute app
C5273 Low cost skin substitute app
C5274 Low cost skin substitute app
C5275 Low cost skin substitute app
C5276 Low cost skin substitute app
C5277 Low cost skin substitute app
C5278 Low cost skin substitute app
C9089 Bupivacaine implant, 1 mg
C9305 Inj, nipocalimab-aahu, 3 mg
C9306 Telisotuzumab vedotin-tllv
C9751 Microwave bronch, 3d, ebus
C9784 Endo sleeve gastro w/tube
G0071 Comm svcs by rhc/fqhc 5 min
G0511 Ccm/bhi by rhc/fqhc 20min mo
G0512 Cocm by rhc/fqhc 60 min mo
G6001 Echo guidance radiotherapy
G6002 Stereoscopic x-ray guidance
G6003 Radiation treatment delivery
G6004 Radiation treatment delivery
G6005 Radiation treatment delivery
G6006 Radiation treatment delivery
G6007 Radiation treatment delivery
G6008 Radiation treatment delivery
G6009 Radiation treatment delivery
G6010 Radiation treatment delivery
G6011 Radiation treatment delivery
G6012 Radiation treatment delivery
G6013 Radiation treatment delivery
G6014 Radiation treatment delivery
G6015 Radiation tx delivery imrt
G6016 Delivery comp imrt
G6017 Intrafraction track motion
G9604 Pt surv results not avail
J0172 Inj, aducanumab-avwa, 2 mg
J0190 Inj biperiden lactate/5 mg
J0200 Alatrofloxacin mesylate
J0205 Alglucerase injection
J0215 Alefacept
J0288 Ampho b cholesteryl sulfate
J0350 Injection anistreplase 30 u
J0365 Aprotonin, 10,000 kiu
J0380 Inj metaraminol bitartrate
J0395 Arbutamine hcl injection
J0710 Cephapirin sodium injection
J0715 Ceftizoxime sodium / 500 mg
J0795 Corticorelin ovine triflutal
J0889 Daprodustat oral 1mg esrd
J1267 Doripenem injection
J1330 Ergonovine maleate injection
J1443 Inj ferric pyrophosphate cit
J1444 Fe pyro cit pow 0.1 mg iron
J1445 Inj triferic avnu 0.1mg iron
J1452 Intraocular fomivirsen na
J1457 Gallium nitrate injection
J1562 Vivaglobin, inj
J1620 Gonadorelin hydroch/ 100 mcg
J1655 Tinzaparin sodium injection
J1710 Hydrocortisone sodium ph inj
J1945 Lepirudin
J2504 Pegademase bovine, 25 iu
J2513 Pentastarch 10% solution
J2910 Aurothioglucose injeciton
J2940 Somatrem injection
J2995 Inj streptokinase /250000 iu
J3280 Thiethylperazine maleate inj
J3305 Inj trimetrexate glucoronate
J3310 Perphenazine injeciton
J3320 Spectinomycn di-hcl inj
J3355 Urofollitropin, 75 iu
J3364 Urokinase 5000 iu injection
J3365 Urokinase 250,000 iu inj
J3400 Triflupromazine hcl inj
J7309 Methyl aminolevulinate, top
J7310 Ganciclovir long act implant
J7513 Daclizumab, parenteral
J8562 Oral fludarabine phosphate
J8650 Nabilone oral
J9019 Erwinaze injection
J9020 Asparaginase, nos
J9098 Cytarabine liposome inj
J9151 Daunorubicin citrate inj
J9165 Diethylstilbestrol injection
J9212 Interferon alfacon-1 inj
J9270 Plicamycin (mithramycin) inj
Q0174 Thiethylperazine maleate10mg
Q2017 Teniposide, 50 mg
Q4100 Skin substitute, nos
Q4106 Dermagraft
Q5109 Injection, ixifi, 10 mg
Q9969 Non-heu tc-99m add-on/dose
S0013 Esketamine, nasal spray
S0080 Injection, pentamidine iseth
S0189 Testosterone pellet 75 mg
J7505 Monoclonal antibodies