S-codes — Temporary National Codes (Non-Medicare)

505 codes — S-codes: Temporary National Codes (non-Medicare)

Codes maintained for use by non-Medicare payers — commercial insurance and state Medicaid plans.

S-codes (S0000-S9999) are maintained by the BlueCross BlueShield Association and used by commercial and Medicaid payers — never by Medicare. They cover services Medicare doesn't pay separately for, services Medicare bundles into other codes, and services that need a temporary code before permanent CPT/HCPCS assignment.

Because S-codes are non-Medicare, claims systems often configure them differently. Always check payer policy before billing — coverage and rates vary widely between commercial insurers and across state Medicaid programs.

Frequently-referenced S-codes:

  • S0257 — Counseling and discussion regarding advance directives
  • S9999 — Sales tax
Code Description
S0012 Butorphanol tartrate, nasal
S0014 Tacrine hydrochloride, 10 mg
S0021 Injection, cefoperazone sod
S0023 Injection, cimetidine hydroc
S0034 Injection, ofloxacin, 400 mg
S0040 Injection, ticarcillin disod
S0078 Injection, fosphenytoin sodi
S0081 Injection, piperacillin sodi
S0088 Imatinib 100 mg
S0090 Sildenafil citrate, 25 mg
S0091 Granisetron 1mg
S0092 Hydromorphone 250 mg
S0093 Morphine 500 mg
S0104 Zidovudine, oral, 100 mg
S0106 Bupropion hcl sr 60 tablets
S0108 Mercaptopurine 50 mg
S0109 Methadone oral 5mg
S0117 Tretinoin topical 5 g
S0119 Ondansetron 4 mg
S0122 Inj menotropins 75 iu
S0126 Inj follitropin alfa 75 iu
S0128 Inj follitropin beta 75 iu
S0132 Inj ganirelix acetat 250 mcg
S0136 Clozapine, 25 mg
S0137 Didanosine, 25 mg
S0138 Finasteride, 5 mg
S0139 Minoxidil, 10 mg
S0140 Saquinavir, 200 mg
S0142 Colistimethate inh sol mg
S0145 Peg interferon alfa-2a/180
S0148 Peg interferon alfa-2b/10
S0155 Epoprostenol dilutant
S0156 Exemestane, 25 mg
S0157 Becaplermin gel 1%, 0.5 gm
S0160 Dextroamphetamine
S0169 Calcitrol
S0170 Anastrozole 1 mg
S0172 Chlorambucil 2 mg
S0174 Dolasetron 50 mg
S0175 Flutamide 125 mg
S0176 Hydroxyurea 500 mg
S0177 Levamisole 50 mg
S0178 Lomustine 10 mg
S0179 Megestrol 20 mg
S0182 Procarbazine, oral
S0183 Prochlorperazine 5 mg
S0187 Tamoxifen 10 mg
S0190 Mifepristone, oral, 200 mg
S0191 Misoprostol, oral, 200 mcg
S0194 Vitamin suppl 100 caps